{"id":3420,"date":"2018-08-20T10:23:39","date_gmt":"2018-08-20T10:23:39","guid":{"rendered":"http:\/\/www.megaflora9.com\/wp\/?p=3420"},"modified":"2018-09-26T06:36:49","modified_gmt":"2018-09-26T06:36:49","slug":"megaflora-9-evo-clinical-evidence","status":"publish","type":"post","link":"https:\/\/megaflora9.com\/?p=3420","title":{"rendered":"Megaflora 9 evo: Clinical evidence"},"content":{"rendered":"<p>Two separate pilot studies have determined the <em>in vivo<\/em>\u00a0survival of <strong>Megaflora 9 evo<\/strong> bacteria.<\/p>\n<h4>Survival of <em>Bifidobacterium<\/em><\/h4>\n<p>In the first study, the survival of <em>Bifidobacterium<\/em> was\u00a0tested in 23 medical students from the University of\u00a0Wageningen. The study was randomized double-blind\u00a0controlled versus placebo with a dosage of 4 g of <strong>Megaflora\u00a09 evo<\/strong> or placebo per day divided in 2 doses for\u00a07 days.<\/p>\n<p>At the beginning and at the end of the study stool samples\u00a0were analyzed by PCR, DGGE and FISH. The results\u00a0showed that students who consumed <strong>Megaflora 9\u00a0evo<\/strong> presented a clear difference in the population of\u00a0bifidobacteria in the faeces compared to the placebo\u00a0group, evidenced by the DGGE profile.<\/p>\n<p>The image shows the DGGE results of nine students,\u00a06 consuming <strong>Megaflora 9 evo<\/strong> (<strong>M9E<\/strong>) and 3 consuming placebo (P). It can be appreciated that students\u00a0M9E-1 and M9E-7 presented specific markers for bifidobacteria\u00a0at day 7 after consumption of <strong>Megaflora\u00a09 ev<\/strong>o compared with baseline (red circles).<\/p>\n<div id=\"attachment_3421\" style=\"width: 814px\" class=\"wp-caption alignnone\"><img aria-describedby=\"caption-attachment-3421\" decoding=\"async\" loading=\"lazy\" class=\" wp-image-3421\" src=\"http:\/\/www.megaflora9.com\/wp\/wp-content\/uploads\/2018\/08\/CLINICAL-1-1024x554.jpg\" alt=\"\" width=\"804\" height=\"435\" srcset=\"https:\/\/megaflora9.com\/wp-content\/uploads\/2018\/08\/CLINICAL-1-1024x554.jpg 1024w, https:\/\/megaflora9.com\/wp-content\/uploads\/2018\/08\/CLINICAL-1-300x162.jpg 300w, https:\/\/megaflora9.com\/wp-content\/uploads\/2018\/08\/CLINICAL-1-768x415.jpg 768w, https:\/\/megaflora9.com\/wp-content\/uploads\/2018\/08\/CLINICAL-1.jpg 1500w\" sizes=\"(max-width: 804px) 100vw, 804px\" \/><p id=\"caption-attachment-3421\" class=\"wp-caption-text\">Profile DGGE to identify the presence of bifidobacteria in faecal samples from students at baseline and 7 days\u00a0of consuming <strong>Megaflora 9 evo<\/strong> or placebo. Red circles show clear differences in the presence of markers in bifidobacteria\u00a0group students <strong>Megaflora 9 evo.<\/strong><\/p><\/div>\n<p>These results demonstrate the survival of <em>Bifidobacterium<\/em>\u00a0of <strong>Megaflora 9 evo<\/strong> in the gastrointestinal tract.<\/p>\n<h4>Survival of <em>Lactobacillus<\/em><\/h4>\n<p>In the second study, 100 medical students from the University\u00a0of Maastricht participated in a randomized double-blind controlled study versus placebo. The students\u00a0were equally divided into two groups that were given\u00a0<strong>Megaflora 9 evo<\/strong> or placebo.<\/p>\n<p>The duration of the study was 8 days during which students\u00a0consumed a dose of 3.8 g of <strong>Megaflora 9 evo<\/strong> or\u00a0placebo divided by 2 times a day. The aim of the study was\u00a0to check the survival of lactobacilli present in the faeces\u00a0after ingestion.<\/p>\n<p>The result showed a significant difference of lactobacilli\u00a0in the faeces of students who consumed <strong>Megaflora 9\u00a0evo<\/strong>, demonstrating the survival of the bacteria after the\u00a0GI passage.<\/p>\n<div id=\"attachment_3422\" style=\"width: 594px\" class=\"wp-caption alignleft\"><img aria-describedby=\"caption-attachment-3422\" decoding=\"async\" loading=\"lazy\" class=\" wp-image-3422\" src=\"http:\/\/www.megaflora9.com\/wp\/wp-content\/uploads\/2018\/08\/CLINICAL-2.jpg\" alt=\"\" width=\"584\" height=\"384\" srcset=\"https:\/\/megaflora9.com\/wp-content\/uploads\/2018\/08\/CLINICAL-2.jpg 1000w, https:\/\/megaflora9.com\/wp-content\/uploads\/2018\/08\/CLINICAL-2-300x197.jpg 300w, https:\/\/megaflora9.com\/wp-content\/uploads\/2018\/08\/CLINICAL-2-768x505.jpg 768w\" sizes=\"(max-width: 584px) 100vw, 584px\" \/><p id=\"caption-attachment-3422\" class=\"wp-caption-text\">Results of the clinical\u00a0study in 100 medical\u00a0students on the survival\u00a0of lactobacilli. Department\u00a0of Microbiology\u00a0at the University of\u00a0Maastricht<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<div class=\"slide-text-bg2\"><span>Two separate pilot studies have determined the in vivo\u00a0survival of Megaflora 9 evo bacteria. Survival of Bifidobacterium In the first study, the survival <\/span><\/div>\n<div class=\"slide-btn-area-sm\"><a href=\"https:\/\/megaflora9.com\/?p=3420\" class=\"slide-btn-sm\">Read More<\/a><\/div>\n","protected":false},"author":3,"featured_media":3423,"comment_status":"closed","ping_status":"closed","sticky":true,"template":"","format":"standard","meta":[],"categories":[32],"tags":[],"_links":{"self":[{"href":"https:\/\/megaflora9.com\/index.php?rest_route=\/wp\/v2\/posts\/3420"}],"collection":[{"href":"https:\/\/megaflora9.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/megaflora9.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/megaflora9.com\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/megaflora9.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3420"}],"version-history":[{"count":3,"href":"https:\/\/megaflora9.com\/index.php?rest_route=\/wp\/v2\/posts\/3420\/revisions"}],"predecessor-version":[{"id":3588,"href":"https:\/\/megaflora9.com\/index.php?rest_route=\/wp\/v2\/posts\/3420\/revisions\/3588"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/megaflora9.com\/index.php?rest_route=\/wp\/v2\/media\/3423"}],"wp:attachment":[{"href":"https:\/\/megaflora9.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3420"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/megaflora9.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3420"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/megaflora9.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3420"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}